COLOTECTTM
Colorectal Cancer
Self-sampling Test
Why early screening of colorectal cancer matters?
Colorectal cancer (CRC) ranks second among repetitive cancers in Hong Kong. In 2019, there were 5,556 new cases, accounting for 15.8% of the total number of new cancer cases in Hong Kong. There were annually 2,174 deaths, which makes it the second cancer killer in Hong Kong second to lung cancer.[1] Colorectal cancer is one of the most preventable forms of cancer.[2] Research shows, when CRC is detected and diagnosed in its early stages, the 5-year relative survival rate is about 90%. [3]
The second highest mortality in the world.
The third highest incidence worldwide.
Risk of CRC increases drastically after the age of 50 years.
Early screening is a vital step in early detection of CRC.
Colorectal cancer screening options
COLOTECTTM Approach
COLOTECTTM is a non-invasive, highly sensitive test for colorectal cancer (CRC) and precancerous lesions. DNA is extracted from stool sample self-collected at home and used for multiplex methylation specific PCR to detect abnormally methylated CRC marker genes ─ SDC2, ADHFE1, and PPP2R5C.
High Specificity 93%
High Sensitivity 88%
Self-sampling at Home
Non-invasive
Short Test Time
Stratified Process
Three Biomarkers Multiplex Complementary Biomarkers
No Additional preparation required
High Specificity
High Sensitivity
Self-sampling at home
Non-invasive
Short Testing Time
Stratified Process
Three Biomarkers Multiplex Complementary biomarkers
No Additional preparation required
Who should be tested for colorectal cancer? [4]
- Individuals aged 50–75 High risk (Biannual)
- Carriers of material gene of HNPCC (age 25 or above)
- Carriers of material gene of FAP(age 12 or above)
How to use COLOTECTTM at home？
What’s inside of the COLOTECTTM Kit ?
1. A sample collection spoon
2. A stool sample tube (with sample preservation buffer inside)
3. A sampling paper
4. A pair of disposable gloves
5. A facial mask
6. A biohazard bag
7. Consent form
8. Instruction manual
COLOTECTTM self-sampling testing process
The stool sample collection kit is collected from designated clinics.
Send the stool sample to the designated clinics, and then it will be sent to the laboratory.
Testing is performed in the lab.
Report is delivered to the customer or attending physician.
Prevent Colorectal Cancer, Practice Healthy Living
References：
[1] Hong Kong Cancer Registry. Overview of Hong Kong Cancer Statistics of 2019.
Available at: https://www3.ha.org.hk/cancereg/pdf/ overview/Overview%20of%20HK%20Cancer %20Stat%202019.pdf
[2] World Cancer Research Fund Hong Kong. Colorectal cancer.
Available at: https://www.wcrf-hk.org/hk-en/preventing-cancer/cancer-types/colorectal-cancer
[3] Colorectal Cancer: Early detection, diagnosis, and staging. American Cancer Society; June 2020.
Available at: https://www.cancer.org/cancer/colon-rectal-cancer/detection-diagnosis-staging/detection.html
[4] World Health Organization. Available at https://www.who.int/news-room/fact-sheets/detail/cancer
[5] Recommendation on Colorectal Cancer Screening. Cancer Expert Working Group On Cancer Prevention and Screening; July 2010.
Available at: https://www.chp.gov.hk/files/pdf/ recommendations_on_crc_screening_ 2010.pdf